Detect Alzheimer's early,
when it can be cured

The first blood diagnosis to detect patients 10 to 20 years before the irreversible symptoms

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A huge challenge to take up

Around 47 million people live with Alzheimer’s worldwide, this costs $800 billion every year and, so far, 100% of clinical trials attempting to find a curative treatment have failed.

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No Diagnosis

Patients are treated 15 years too late due to the lack of an early diagnosis.

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Irrelevant Animal Models

Animal models used to select drug candidates do not fully replicate the human disease.

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No Cure

Currently approved medications do not change the progression of the disease.

Tackling Alzheimer's during the silent phase

Drug development in the field of Alzheimer’s disease is certainly among the most challenging and has been suffering dramatic setback regardless of the strategy developed. For 30 years, we targeted a stage of the disease which was too late to restore the cognitive impairment.
We need to detect patients 15 to 20 years before the onset of these irreversible symptoms to find an effective treatment.

The first blood diagnosis of the silent phase

Combining machine learning and neuroscience, AgenT is developing specific blood biomarkers combinations for each stage of the disease. Our algorithm will allow us to detect patients during the silent phase of Alzheimer's and stratify them according to the disease progression.
AgenT diagnosis will pave the way for a personalized medicine to prevent Alzheimer's dementia.

  • Universal blood test
  • Free from invasives procedures
  • 3 stages of progression to tailored the treatment to each patient

It's time to target the silent phase of Alzheimer's disease !

Publications

Alzheimer’s disease-like APP processing in wild-type mice identifies synaptic defects as initial steps of disease progression

Audrain et al. January 2016

βAPP Processing Drives Gradual Tau Pathology in an Age-Dependent Amyloid Rat Model of Alzheimer’s Disease

Audrain et al. October 2018

Is it time to rethink the Alzheimer’s disease drug development strategy by targeting its silent phase?

Souchet et al. February 2018

Meet the team

Jérôme Braudeau, PhD

Cofounder & CEO

Baptiste Billoir

Cofounder & CFO

Benoît Souchet, PhD

CSO

Advisory Board

Stéphane Epelbaum, MD

Neurologist
IM2A, Pitié-Salpêtrière Hospital

Laurent Meijer, PhD

CEO & CSO
ManRos Therapeutics

Yannick Pletan, MD

Chief Medical Officer
Acticor Biotech

Bernard Meunier, PhD

Former President of the French Academy of Sciences

Claude Hennion, PhD

Founder & CEO
Oncodiag

Nicolas Vayatis, PhD

Head of the CMLA UMR 8536, ENS Paris-Saclay & CNRS

They support us

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You can contact us with anything related to our company. We'll get in touch with you as soon as possible.

Contact Information

STATION F, Founders Program
5 Parvis Alan Turing
75013 Paris, France

Phone: +33 6 66 43 90 61

Email: hello@agent-biotech.com